An experimental scleroderma treatment uses immune cells with changed genes. Early data will be presented Nov. 8.
CRISPR Therapeutics (CRSP) will present Phase 1 clinical data for its investigational gene-edited immune-cell therapy, zugocabtagene geleucel (zugo-cel), in patients with refractory systemic sclerosis. The presentation will occur at the American College of Rheumatology (ACR) Convergence 2026 on November 8, 2026, at 10:30 a.m. ET. Zugo-cel targets CD19 and is currently being evaluated in Phase 1 trials for various autoimmune indications.
CRISPR Therapeutics to Present Clinical Data on Zugocabtagene Geleucel (Zugo-cel) in Autoimmune Disease at the American College of Rheumatology (ACR) Convergence 2026
CRISPR Therapeutics announced it will present Phase 1 clinical data for its investigational gene-edited CAR T cell therapy, zugocabtagene geleucel (zugo-cel), at the American College of Rheumatology (ACR) Convergence 2026. The presentation will highlight the safety and efficacy of zugo-cel in patients with refractory systemic sclerosis. Zugo-cel is currently being evaluated in Phase 1 trials for various autoimmune diseases.
Total common shares outstanding of CRISPR Therapeutics AG – HAN:1CG
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Pretax income of CRISPR Therapeutics AG – HAN:1CG
This article provides financial information for CRISPR Therapeutics AG (HAN:1CG) on the Hannover Stock Exchange, specifically focusing on its pretax income. The content highlights the company's financial overview and includes various links to market data, trading tools, and community resources provided by TradingView.
CRISPR Therapeutics stock price target reaffirmed at $80 by Citizens
Citizens has reaffirmed its Market Outperform rating and $80 price target for CRISPR Therapeutics (NASDAQ: CRSP). The firm highlights CRISPR's success in commercializing a gene-editing cell therapy and its pipeline of late-stage assets, particularly in cardiovascular and metabolic indications. Key early readouts for CTX310, CTX611, and Zugo-cel are anticipated in the second half of 2026.
Form 144 CRISPR THERAPEUTICS AG For: 27 September By Investing.com
This article announces the filing of Form 144 for CRISPR THERAPEUTICS AG on September 27th, as reported by Investing.com. It is a brief, informational piece without additional details about the Form 144 filing itself. The article also includes various market data, news headlines, and advertising typical of a financial news platform.
Form 144 CRISPR THERAPEUTICS AG For: 27 September By Investing.com
This article reports on a Form 144 filing for CRISPR THERAPEUTICS AG (CRSP) on September 27. It notes that the stock was down 2.64% at the time of publication. The brief report primarily serves as a notification of the SEC filing.
CRISPR Therapeutics' Casgevy sales jump 78% in Q2, boosting long-term buy case despite AI gene editing risks
CRISPR Therapeutics' gene therapy Casgevy saw a 78% sequential sales increase in Q2, reinforcing its potential as a blockbuster drug despite initial market skepticism. Although new AI-driven gene editing technologies pose competitive risks, they are not expected to impact clinical outcomes soon. The company's strong pipeline and management execution continue to make it a favorable long-term buy, with 100% of investor activity on the buy side as of September 25, 2026.
CRISPR Therapeutics (CRSP) counsel exercised options and sold 10,400 shares under a trading plan.
James R. Kasinger, General Counsel and Secretary of CRISPR Therapeutics AG (CRSP), exercised options for 10,400 common shares at $13.62 per share and simultaneously sold these 10,400 shares at a weighted average price of $60.2365 per share on September 22, 2026. This transaction was conducted under a Rule 10b5-1 trading plan established on May 6, 2026. After these transactions, Kasinger holds 83,232 stock options and 94,784 common shares.
CRISPR Therapeutics (NASDAQ:CRSP) General Counsel James Kasinger Sells 10,400 Shares of Company Stock
CRISPR Therapeutics General Counsel James Kasinger sold 10,400 shares of the company's stock for $626,496, reducing his stake by 9.89%. The stock, trading at $55.70, has a market capitalization of $5.39 billion. Analysts maintain a "Moderate Buy" rating with an average price target of $67.94 for CRSP.
CRISPR Therapeutics AG (CRSP) Options Chain - Yahoo Finance
This Yahoo Finance page displays the options chain for CRISPR Therapeutics AG (CRSP) as of September 25, with data delayed by 15 minutes. It lists both call and put options with an expiration date of October 9, 2026, showing strike prices, last trade dates, last prices, and implied volatility. The article also provides current stock price information for CRSP, as well as general market data for Canadian and international markets.
Autologous Hematopoietic Stem Cell Gene Therapy Market Global Report 2026: A $13.44 Billion Market by 2030 as Novartis, Vertex, CRISPR Therapeutics and Orchard Therapeutics Accelerate the Gene-Editing Race
The global autologous hematopoietic stem cell gene therapy market is projected to grow significantly, reaching $13.44 billion by 2030 from $5.23 billion in 2025, driven by advancements in gene-editing, increased investment in rare disease treatments, and personalized therapies. Key growth factors include commercialization of gene-editing therapies, regulatory approvals, adoption of personalized medicine, and infrastructure investments. North America was the largest regional market in 2025, with Asia-Pacific expected to be the fastest-growing region.
CRISPR Therapeutics AG (CRSP) Stock Moves 1.20%: What You Should Know
CRISPR Therapeutics AG (CRSP) closed up 1.2% at $59.03, outperforming the Medical sector and S&P 500 over the past month. The company is projected to report a 9.4% increase in EPS and a 971.24% rise in revenue for its upcoming earnings release. Analysts maintain a "Hold" rating (Zacks Rank #3) for CRSP, indicating optimism in its business and profitability based on recent estimate revisions.
Insider plans $626K CRISPR Therapeutics (NASDAQ: CRSP) stock sale
An insider at CRISPR Therapeutics AG (CRSP), James Ramon Kasinger, has filed a Rule 144 notice to sell 10,400 common shares on NASDAQ. The aggregate value of these shares is approximately $626,459.60, with the planned sale date being September 22, 2026, executed through Morgan Stanley Smith Barney LLC. This filing signals an intent for a potential sale by an affiliate rather than a transaction by the company itself.
Director at CRISPR Therapeutics (CRSP) gets stock in no-cash fund distribution
CRISPR Therapeutics director Ali Behbahani reported receiving 75 common shares of CRSP through a pro rata distribution from NEA Partners 15, L.P. and a related trust on August 6, 2025. This transaction, which involved no monetary consideration, increased his direct holdings to 316 shares and indirect holdings (via The Ali Behbahani Revocable Trust) to 29 shares. The Form 4 filing clarified that Behbahani disclaims beneficial ownership of trust shares in which he has no pecuniary interest and that no Rule 10b5-1 trading plan was involved.
Ali Behbahani Sells 13,679 Shares of CRISPR Therapeutics (NASDAQ:CRSP) Stock
Ali Behbahani, a director at CRISPR Therapeutics, sold 13,679 shares of NASDAQ:CRSP stock for over $780,000, reducing his position by 45.12%. Despite this insider selling, the stock rose 3.1%, and analysts maintain a "Moderate Buy" rating with an average price target of $67.94. The company reported a quarterly loss and analysts expect a full-year loss, while institutional investors hold a significant 69.2% stake.
Why CRISPR Therapeutics (CRSP) Is Back In The Spotlight
CRISPR Therapeutics (CRSP) is regaining investor attention ahead of a major healthcare conference, showcasing its gene editing pipeline. Despite recent short-term gains, the stock has experienced mixed longer-term performance. Simply Wall St's analysis suggests CRISPR Therapeutics is undervalued based on discounted cash flow (DCF) models, even though its Price-to-Book (P/B) ratio indicates moderate valuation compared to peers.
3 Reasons CRISPR Therapeutics Stock Is Still a Buy After a Rocky 2026
CRISPR Therapeutics stock has had a disappointing performance recently, but the company's gene-editing drug, Casgevy, is accruing revenue set to be reported next year. Beyond Casgevy, CRISPR Therapeutics has a promising pipeline of other treatments and its patented gene-editing technology has significant long-term potential. These factors suggest the stock remains an attractive investment for those comfortable with the inherent risks of biotech.
Reynders McVeigh Capital Management LLC Sells 92,373 Shares of CRISPR Therapeutics AG $CRSP
Reynders McVeigh Capital Management LLC significantly reduced its stake in CRISPR Therapeutics AG (NASDAQ:CRSP) by 74.8% in the second quarter, selling 92,373 shares and retaining 31,065 shares valued at $1.69 million. This occurred as CRISPR Therapeutics shares fell 2.1% to $51.83, with the company reporting a quarterly loss of $0.94 per share on $10.18 million in revenue. Despite institutional investors owning 69.2% of the stock, analysts maintain a "Moderate Buy" consensus rating with an average price target of $68.06.
CRISPR Therapeutics Eyes CASGEVY Growth, Year-End Pipeline Catalysts
CRISPR Therapeutics is focusing on expanding the adoption of CASGEVY, particularly following its FDA approval for patients aged 2 and older, with pediatric treatments and shorter conditioning regimens expected to drive growth. The company anticipates significant data catalysts by the end of 2026, including Phase 1b results for CTX310 in severe hypertriglyceridemia, Phase 2 data for Factor XI therapy CTX611, and further updates from its zugo-cel autoimmune program. Additionally, CRISPR Therapeutics is advancing earlier-stage gene-editing technologies, such as in vivo editing and whole-gene insertion, with more clinical data anticipated in 2027.
CRISPR Therapeutics to Present at the Morgan Stanley 24th Annual Global Healthcare Conference
CRISPR Therapeutics announced its senior management team will present at the Morgan Stanley 24th Annual Global Healthcare Conference on September 14, 2026, at 1:05 p.m. EST. A live webcast and subsequent replay will be available on the company's investor relations website. The company, an industry leader in gene-editing with the first CRISPR-based therapy approval, is advancing a diversified pipeline and expanding its gene editing toolkit.
CRISPR Therapeutics to Present at the Morgan Stanley 24th Annual Global Healthcare Conference
CRISPR Therapeutics announced that its senior management team will present at the Morgan Stanley 24th Annual Global Healthcare Conference on September 14, 2026, at 1:05 p.m. EST. A live webcast of the fireside chat will be available on the company's investor relations website, with a replay archived for 14 days. The company, known for developing the world's first CRISPR-based therapy, CASGEVY®, continues to advance a broad pipeline across various diseases.
Raiffeisen Bank International AG Buys Shares of 20,000 CRISPR Therapeutics AG $CRSP
Raiffeisen Bank International AG acquired 20,000 shares of CRISPR Therapeutics AG (NASDAQ:CRSP) in the second quarter, valued at approximately $1.13 million. Institutional investors now own 69.2% of the company, which recently reported a quarterly loss of $0.94 per share on $10.18 million in revenue. Despite a 1.2% stock decline and a trading range between $44.12 and $78.48, analysts maintain a "Moderate Buy" consensus with an average price target of $68.06.
Shah Wealth Advisors LLC Buys New Position in CRISPR Therapeutics AG $CRSP
Shah Wealth Advisors LLC has acquired a new position in CRISPR Therapeutics AG (NASDAQ:CRSP), purchasing 69,060 shares valued at approximately $3.77 million, representing 0.9% of its portfolio. Institutional investors collectively own 69.2% of the company, which holds a "Moderate Buy" consensus rating and an average price target of $68.06 from analysts. CRISPR Therapeutics recently reported a quarterly loss of $0.94 per share on $10.18 million in revenue, with analysts anticipating a full-year loss of $4.47 per share.
Crispr Therapeutics: Casgevy Validates The Platform, Strengthening The Acquisition Case
CRISPR Therapeutics has transitioned to a commercial stage company with the FDA approval of CASGEVY, validating its CRISPR/Cas9 platform. The company's pipeline targets significant markets in cardiovascular, autoimmune, oncology, and diabetes, supported by strong intellectual property and partnerships with major pharmaceutical companies. Despite its early-stage pipeline and execution risks, the company's current market capitalization of $5.6 billion and $1.78 billion net cash position make it an attractive acquisition target, particularly below a $52 valuation.
Citizens reiterates CRISPR Therapeutics stock rating on gene therapy data By Investing.com
Citizens has reiterated its Market Outperform rating and $80.00 price target for CRISPR Therapeutics (NASDAQ:CRSP) shares. This affirmation follows positive data presented on CTX310, an in vivo gene editor, which showed lasting impact on ANGPTL3 expression and cardiovascular biomarkers, supporting its advancement to Phase 1b trials. The firm's positive outlook is also bolstered by recent FDA label expansion for CASGEVY and progress in CRISPR Therapeutics' pipeline.
CRISPR Therapeutics' (CRSP) Market Outperform Rating Reiterated at Citizens Jmp
Citizens Jmp has reiterated its "market outperform" rating for CRISPR Therapeutics (CRSP) with an $80 price target, indicating a potential 38.6% upside. The company currently holds a "Moderate Buy" consensus rating from analysts, with an average price target of $68.06. CRISPR Therapeutics reported a quarterly loss of $0.94 per share on $10.18 million in revenue, and institutional investors own approximately 69.2% of its stock.
CRISPR Therapeutics (NASDAQ:CRSP) Earns Buy Rating from Needham & Company LLC
Needham & Company LLC reaffirmed a "buy" rating for CRISPR Therapeutics (NASDAQ:CRSP) and set an $82 price target, indicating a potential 42.07% upside. This aligns with a broader "Moderate Buy" consensus rating among analysts and an average target price of $68.06. The company recently reported quarterly revenue of $10.18 million and a loss of $0.94 per share, with institutional investors owning a significant portion of its stock.
Citizens reiterates CRISPR Therapeutics stock rating on gene therapy data
Citizens reiterated a Market Outperform rating and an $80.00 price target for CRISPR Therapeutics (NASDAQ:CRSP) following positive data for its gene editor CTX310 and recent FDA label expansion for CASGEVY. The CTX310 data showed lasting impact on ANGPTL3 expression and cardiovascular biomarkers, supporting advancement to Phase 1b trials. Analysts maintain a consensus Buy rating, with potential market expansion and upcoming data releases expected to further impact the company's prospects.
Clinical: Single CRISPR Infusion Keeps Lipids Low for a Year
A single intravenous infusion of CRISPR-Cas9 therapy CTX310 from CRISPR Therapeutics effectively lowered circulating ANGPTL3, triglycerides, and LDL cholesterol for a full year in 15 adults with lipid disorders resistant to standard treatments. The phase 1a trial reported no dose-limiting toxicity or new treatment-related adverse events during the one-year follow-up. This therapy aims to pharmacologically reproduce the benefits of naturally occurring loss-of-function variants in ANGPTL3, which are associated with reduced atherosclerotic cardiovascular risk.
CRISPR Therapeutics Presents Phase 1a Data for CTX310® Demonstrating Deep and Durable ANGPTL3 Editing, Triglyceride and LDL Lowering at ESC Congress 2026
CRISPR Therapeutics presented Phase 1a clinical trial data for CTX310®, an investigational CRISPR/Cas9 gene editing therapy, at the ESC Congress 2026. The data demonstrated deep and durable reductions in ANGPTL3, triglycerides, and LDL cholesterol, sustained for one year after a single dose, with good tolerability. These findings, also published in The New England Journal of Medicine, support CTX310's potential for long-lasting treatment of cardiometabolic diseases, with further updates from the Phase 1b trial expected in late 2026.
CRISPR Therapeutics Shares Advance 5.8% Ahead of CTX310 Results Release
CRISPR Therapeutics (NASDAQ:CRSP) saw its shares climb 5.8% ahead of the anticipated release of CTX310 clinical trial results on August 28th. The company holds a strong financial position with $2.36 billion in cash and securities, supporting its continued research and development despite being cash flow negative. Analysts from Citizens maintain an "Outperform" rating with an $80 price target, highlighting the potential for CTX310 as a "truly differentiated, one-time therapy" for severe triglyceride and cholesterol conditions.
CRISPR Therapeutics (NASDAQ:CRSP) Earns Market Outperform Rating from Citizens Jmp
Citizens Jmp has reissued a "market outperform" rating for CRISPR Therapeutics (NASDAQ:CRSP) and set an $80 price target, suggesting a 40.15% upside. This positive outlook aligns with a "Moderate Buy" consensus rating from analysts, though the stock recently reported a quarterly loss of $0.94 per share. Institutional investors hold a significant 69.20% stake in the company.
CRISPR Therapeutics (CRSP) Rallies On Pipeline Focus, Is The 73% Discount Too Hard To Ignore?
CRISPR Therapeutics (CRSP) has seen a recent rally, with its stock closing at $59.50, reflecting a 27.85% return over the past month. Despite a 5-year decline of 51.94%, the company, which focuses on gene-based medicines, is estimated by a Simply Wall St DCF model to have an intrinsic value of $220.94, suggesting a 73.1% discount. The article explores whether this significant discount signals an investment opportunity or justifies market caution due to the company's ongoing losses and long development timelines for its pipeline.
CRISPR Therapeutics (CRSP): Orbis-led investors disclose 5.6% ownership stake
Orbis Investment Management Ltd and Allan Gray Australia Pty Ltd have disclosed a combined beneficial ownership of 5,449,161 shares, or 5.6%, of CRISPR Therapeutics AG (CRSP) Common Stock as of June 30, 2026. Orbis holds the vast majority of these shares with sole voting and dispositive power, while Allan Gray Australia holds a smaller portion, also with sole voting and dispositive power. Both entities disclaim being part of a group for beneficial ownership purposes.
Stronger Revenue and Narrower Loss Might Change The Case For Investing In CRISPR Therapeutics (CRSP)
CRISPR Therapeutics (CRSP) reported improved Q2 2026 results with rising revenue and a narrower net loss, offering some relief regarding its cash burn. While these results strengthen the company's position, the market views them as helpful but not thesis-changing, as the core investment narrative still hinges on the eventual success of its gene-editing pipeline and commercial uptake. Investors should consider the impact of sustained losses on future funding needs and weigh various fair value estimates.
Stronger Revenue and Narrower Loss Might Change The Case For Investing In CRISPR Therapeutics (CRSP)
CRISPR Therapeutics (CRSP) reported improved Q2 2026 results, with revenue rising to US$10.18 million and net loss narrowing to US$91.15 million. While these results slightly ease concerns about cash burn and progress, the investment narrative still hinges on the success of its gene-editing pipeline, clinical readouts, and commercial uptake. The market views these improvements as helpful but not yet thesis-changing, with fair value estimates varying significantly among investors.
Bank of America Corp DE Decreases Stock Position in CRISPR Therapeutics AG $CRSP
Bank of America Corp DE reduced its stake in CRISPR Therapeutics AG by 10.4% in the first quarter, selling 113,815 shares and retaining 983,072 shares valued at $46.765 million. Institutional investors collectively own 69.2% of the company, which reported a quarterly loss of $0.94 per share on $10.18 million in revenue, with analysts projecting a full-year loss of $4.53 per share. Despite ongoing losses, analysts maintain a "Moderate Buy" consensus rating with an average price target of $68.06.
CRISPR Therapeutics (CRSP) Stock Looks Fairly Valued Despite Pipeline Promise
CRISPR Therapeutics (CRSP) stock has seen a significant decline over the past five years but now appears to be fairly valued. Despite promising allogeneic CAR-T programs, its Price-to-Book ratio is in line with the biotech industry average, suggesting investors acknowledge its potential without pricing in overly optimistic outcomes. The company's future valuation will largely depend on its ability to translate research into viable products while maintaining its financial stability.
Stronger Revenue and Narrower Loss Might Change The Case For Investing In CRISPR Therapeutics (CRSP)
CRISPR Therapeutics (CRSP) recently reported improved Q2 2026 results with rising revenue of US$10.18 million and a narrower net loss of US$91.15 million, easing immediate cash burn concerns. While these results strengthen the company's position for future clinical and regulatory milestones, they haven't fundamentally altered the market's investment thesis, which remains focused on the long-term success of its gene-editing pipeline. Investors should consider diverse fair value estimates and the impact of sustained losses on future funding.
CRISPR Therapeutics (CRSP) CFO Prasad Raju makes bona fide gift of 750 shares
CRISPR Therapeutics AG's Chief Financial Officer, Prasad Raju, reported a bona fide gift of 750 Common Shares on August 7, 2026. This transaction is classified as a disposition, and following the gift, Raju directly holds 14,815 Common Shares. The Form 4 filing indicates the transfer was a gift with a reported price of $0.00 per share and was not made under a Rule 10b5-1 plan.
CRISPR Therapeutics AG (CRSP) Stock Forecasts
This article provides an analyst report from Morningstar on CRISPR Therapeutics AG (CRSP), noting that its gene-editing therapy Casgevy is gaining traction despite initial commercial hurdles. The report highlights the company's focus on CRISPR/Cas9-based therapeutics. It also includes various market data and related analyst reports for other companies.
CRISPR Therapeutics AG $CRSP Stock Position Raised by Quantinno Capital Management LP
Quantinno Capital Management LP significantly increased its stake in CRISPR Therapeutics AG (NASDAQ:CRSP) by 613.5% in the first quarter, now owning 47,989 shares valued at $2.28 million. Institutional investors hold 69.2% of the company, and analysts maintain a "Moderate Buy" rating with an average price target of $68.06. The company reported a quarterly loss of $0.94 per share on $10.18 million in revenue, while continuing development of its CRISPR/Cas9 gene-editing therapies.
CRISPR Therapeutics (CRSP) Earnings Drew Fresh Interest, Is The Stock Below Fair Value?
CRISPR Therapeutics (CRSP) reported improved Q2 2026 results with higher revenue and a reduced net loss, leading to a short-term stock rebound. Despite mixed long-term performance, a discounted cash flow (DCF) model suggests the stock is significantly undervalued at $53.52 compared to a fair value of $218.96. However, its Price-to-Book ratio is higher than the industry average, presenting a mixed valuation picture for investors.
CRISPR Therapeutics (NASDAQ:CRSP) Rating Increased to Hold at Wall Street Zen
Wall Street Zen has upgraded CRISPR Therapeutics (CRSP) from a "Sell" to a "Hold" rating, while the broader analyst consensus remains a "Moderate Buy" with an average target price of $68.06. Despite a recent 3.6% increase in share price, the company reported a quarterly loss of $0.94 per share. Institutional ownership is high at 69.2%, though one insider sold shares to cover tax obligations.
RBC Capital Keeps Their Hold Rating on Crispr Therapeutics AG (CRSP)
RBC Capital has maintained its Hold rating on Crispr Therapeutics AG (CRSP) with a price target of $50.00. This comes as Crispr Therapeutics reported a quarterly revenue of $10.18 million and a GAAP net loss of $91.15 million in its latest earnings release. The company has an analyst consensus of Moderate Buy with a higher price target consensus of $72.64, indicating a potential 46.54% upside.
Goldman Sachs Keeps Their Hold Rating on Crispr Therapeutics AG (CRSP)
Goldman Sachs has reiterated a Hold rating for Crispr Therapeutics AG (CRSP) with a price target of $55.00. This follows similar Hold ratings from other analysts like Wells Fargo, though H.C. Wainwright maintained a Buy rating. The company recently reported quarterly revenue of $10.18 million and a GAAP net loss of $91.15 million.
Brave Asset Management Inc. Cuts Stake in CRISPR Therapeutics AG $CRSP
Brave Asset Management Inc. significantly reduced its stake in CRISPR Therapeutics AG (NASDAQ:CRSP) by 67.7% in the second quarter, now owning 11,234 shares worth $613,000. This comes amidst mixed activity from other institutional investors and varying analyst ratings for the gene-editing company. CRISPR Therapeutics recently posted earnings of ($0.94) EPS and $10.18 million in revenue for the quarter, with analysts expecting a negative EPS for the current year.
Dimensional Fund Advisors LP Sells 412,889 Shares of CRISPR Therapeutics AG $CRSP
Dimensional Fund Advisors LP significantly reduced its stake in CRISPR Therapeutics AG by 45.5% in the first quarter, selling 412,889 shares. Following the sale, the firm now owns 494,218 shares valued at $23.49 million. The article also covers recent analyst ratings, insider trading activity, and CRISPR Therapeutics' financial performance and pipeline developments.
Why CRISPR Therapeutics (CRSP) Is Up 11.6% After CASGEVY Expansion And Pipeline Updates - And What's Next
CRISPR Therapeutics (CRSP) saw its stock rise by 11.6% following its second-quarter 2026 results, which included an increase in revenue to US$10.18 million, a narrowed net loss, and the expansion of CASGEVY's FDA approval to younger children. The company also announced new in vivo trials in cardiovascular, autoimmune, and oncology indications, strengthening its investment narrative despite ongoing losses and funding risks. While the stock has seen limited movement over three years, these updates provide new near-term catalysts, though core uncertainties regarding long-term adoption and clinical success remain.