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| Date | Name | Title | Action | No Shares | Price Per Share |
|---|---|---|---|---|---|
Insider Transactions For IONS | |||||
| 2026-02-13 | Swayze, Eric | EVP Research | Sold | 6207 | $82.07 |
| 2026-02-13 | Swayze, Eric | EVP Research | Sold | 9435 | $81.56 |
| 2026-02-11 | Parshall, B Lynne | Director | Sold | 5000 | $82.72 |
| 2026-02-06 | Monia, Brett P | Director, Chief Executive Officer | Sold | 29430 | $85.79 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 16463 | $0.00 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 16463 | $83.03 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Purchased | 16463 | $32.60 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 48626 | $83.03 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Purchased | 48626 | $60.89 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 48626 | $0.00 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 20000 | $82.60 |
| 2026-02-02 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 0 | $0.00 |
| 2026-01-30 | Birchler, Brian | EVP, Corp and Development Ops | Sold | 6179 | $83.03 |
| 2026-01-30 | Schneider, Eugene | EVP, Chf Clinical Develop Ofcr | Sold | 6179 | $83.45 |
| 2026-01-30 | Monia, Brett P | Director, Chief Executive Officer | Sold | 62970 | $82.72 |
| 2026-01-30 | Swayze, Eric | EVP Research | Sold | 6179 | $82.93 |
| 2026-01-30 | Hougen, Elizabeth L | EVP, Finance & CFO | Sold | 6988 | $83.24 |
| 2026-01-30 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 5885 | $82.95 |
| 2026-01-30 | O'neil, Patrick R. | EVP CLO & General Counsel | Sold | 6179 | $83.53 |
| 2026-01-30 | Baroldi, Joseph | EVP, Chief Business Officer | Sold | 5296 | $82.96 |
