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| Date | Name | Title | Action | No Shares | Price Per Share |
|---|---|---|---|---|---|
Insider Transactions For IONS | |||||
| 2026-07-31 | Hayden, Michael R | Director | Purchased | 5000 | $51.60 |
| 2026-07-30 | Hayden, Michael R | Director | Purchased | 15000 | $53.38 |
| 2026-07-15 | Berthelsen, Spencer R | Director | Purchased | 5220 | $0.00 |
| 2026-07-15 | Berthelsen, Spencer R | Director | Sold | 5220 | $0.00 |
| 2026-07-15 | Herman, Joan E | Director | Purchased | 5220 | $0.00 |
| 2026-07-15 | Herman, Joan E | Director | Sold | 5220 | $0.00 |
| 2026-07-15 | Reikes, Peter N | Director | Purchased | 3399 | $0.00 |
| 2026-07-15 | Hantson, Ludwig | Director | Purchased | 3399 | $0.00 |
| 2026-07-07 | Kordasiewicz, Holly B. | EVP, Chief Development Officer | Sold | 362 | $84.30 |
| 2026-07-07 | Diaz, Allene M. | Director | Purchased | 10111 | $47.11 |
| 2026-07-07 | Diaz, Allene M. | Director | Sold | 10111 | $85.42 |
| 2026-07-07 | Diaz, Allene M. | Director | Sold | 10111 | $0.00 |
| 2026-07-07 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 15000 | $85.46 |
| 2026-07-07 | Bennett, C Frank | EVP, Chief Scientific Officer | Purchased | 15000 | $0.00 |
| 2026-07-07 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 5536 | $83.58 |
| 2026-07-07 | Bennett, C Frank | EVP, Chief Scientific Officer | Sold | 15000 | $0.00 |
| 2026-07-01 | Loscalzo, Joseph | Director | Purchased | 2301 | $0.00 |
| 2026-07-01 | Klein, Joseph Iii | Director | Purchased | 11518 | $39.94 |
| 2026-07-01 | Klein, Joseph Iii | Director | Sold | 99 | $79.45 |
| 2026-07-01 | Klein, Joseph Iii | Director | Sold | 11419 | $79.04 |
